Clinical oncology crosses paths with many fields, including cardiology. Annual increase in cancer and cardiovascular disease incidence is associated with increasing life expectancy. Cancer risk in patients with treated cardiovascular diseases increases with age. An estimated 6% of cancer patients in Russia do not receive treatment because of a comorbidity. The principal goal in case of comorbidities is to determine severity of the main and competing diseases and follow a step-by-step treatment approach. Issue 2 (Vol 27) focuses on original studies and a case series demonstrating results of cardiovascular disease diagnosis and treatment in cancer patients.