ONCOLOGY
Published 2012-09-25
Keywords
- STEREOTACTIC RADIOTHERAPY,
- HYPOFRACTIONATED,
- TOXICITY,
- DOSE ESCALATION,
- DOSE TO NORMAL TISSUE
How to Cite
Anikeeva, O., Samoylova, Y., Filatov, P., & Pashkovskaya, O. (2012). Hypofractionated stereotactic radiotherapy for malignant tumors of the lung. Patologiya Krovoobrashcheniya I Kardiokhirurgiya, 16(3), 61–66. https://doi.org/10.21688/1681-3472-2012-3-61-66
Copyright (c) 2012 Anikeeva O.Yu., Samoylova Ye.A., Filatov P.V., Pashkovskaya O.A.

This work is licensed under a Creative Commons Attribution 4.0 International License.
Abstract
Hypofractionated stereotactic radiotherapy was used for 26 patients at medically inoperable stage I of non-small cell lung cancer with dose escalation of 48-54 Gy prescribed at 90 or 95% isodose level in 3-4 fractions. Nine-months local control and cancer-specific survival were 82.0 and 66.8% respectively, with minimal toxicity. For metastatic lung tumors local control was obtained in 92% cases. Hypofractionated stereotactic radiation therapy (SBRT) is safe and feasible for the treatment of inoperable primary lung cancer and single lung metastasis.References
- Чисов В.И. Онкология: национальное руководство. М., 2008. C. 128-168.
- Brown W.T. et al. // Comput. Aided. Surg. 2007. V. 12 (5). P. 253-261.
- Charlson M.E., Pompei P., Ales K.L., MacKenzie C.R. // J. Chronic Dis. 1987. V. 40. P. 373-383.
- Sawada S., Komori E., Yamashita M. et al. // Surg. Endosc. 2007. V. 21. P. 1607-1611.
- Kong F.M., Ten Haken R.K., Schipper M.J. et al. // Int. J. Rad. Oncol. Biol. Phys. 2005. V. 63. P. 324-333.
- Jeremic B., Brady L.W. et al. Radiation Oncology. 2011.
- Brock J., Ashley S., Bedford J. et al. // Clinical Oncology. 2008. V. 20 (9). P. 666-676.
- Bezjak А., Bradley J., Gaspar L. et al. // J. Radiat. Oncol. Biol. Phys. 2011. V. 61. P. 123-1210.
- Fenwick J.D., Nahum A.E., Malik Z.I. et al. // Clin. Oncol. 2009 DOI:10.1016/j.clon.2008.12.01
- Пасов В.В., Зубова Н.Д., Иволгин Е.М. // Сибирский онкологический журнал. 2009. № 6 (36). С. 58-61.
- Giraud P. et al. // Lung. Cancer. 2006. V. 51 (1). Р. 41-51.
- Panakis N., McNair H.A., Christian J.A. et al. // Radiother. Oncol. 2008. V. 87. Р. 65-73.
- Wulf J., Haedinger U., Oppitz U. et al. // Int. J. Rad. Oncol. Biol. Phys. 2004. V. 60. P. 186-196.
- Rodrigues G., Lock M., D'Souza D. et al. // Radiother. Oncol. 2004. V. 71. Р. 127-138.
- Кутузова А.Б., Лелюк В.Г., Гуськова А.К. // Медицинская радиология и радиационная безопасность. 2000. Т. 47, № 3. С. 66-79.