Vol. 19 No. 2 (2015)
CORONARY ARTERY DISEASES

Assessment of the mechanical function of the left atrium in patients with ischemic mitral regurgitation

S. Soukhanov
Federal Center for Cardiovascular Surgery, 35 Marshal Zhukov Str., Perm, 614000, Russian Federation
Bio
E. Orekhova
Federal Center for Cardiovascular Surgery, 35 Marshal Zhukov Str., Perm, 614000, Russian Federation
Bio
T. Matanovskaya
Federal Center for Cardiovascular Surgery, 35 Marshal Zhukov Str., Perm, 614000, Russian Federation
Bio

Published 2015-10-08

Keywords

  • ischemic mitral regurgitation,
  • left atrium function

How to Cite

Soukhanov, S., Orekhova, E., & Matanovskaya, T. (2015). Assessment of the mechanical function of the left atrium in patients with ischemic mitral regurgitation. Patologiya Krovoobrashcheniya I Kardiokhirurgiya, 19(2), 55–62. https://doi.org/10.21688/1681-3472-2015-2-55-62

Abstract

Objective. The study was designed to investigate LA mechanical aspects in patients with IMR by using a vector analysis of endocardium movement.
Methods. 92 CHD patients aged 57.16±10.31 years, with 63 of them being males (68%), were treated at our center over a period of 2013-2014. The inclusion criteria were: hemodynamically relevant damage of coronary arteries during coronary angiography, I-III stage IMR according to echocardiography, sinus rhythm of 60-89 beats per minute during examination and good quality of echocardiographic visualization of endocardial LA.
Results. A strong direct correlation between MP and SR at LA systole (RS=0.84) and MP and SR at LA at the conduit phase was revealed. A reverse correlation of MP and SR occurred at the soaking phase (RS= -0.8) and at the reservoir phase (RS= -0.8). LA longitudinal systolic deformation was significantly low at the contractile phase (patients with МР -6.2±4.4% vs -12±2.1% in the control group, р<0.05) and at the soaking phase (patients with МР -1±0.56% vs -0.4±0.5% in the control group, р<0.05).
Conclusion. The research shows that LA mechanical function indicators are associated with ischemic mitral failure. Changes in LA deformation and deformation speed reflect the relationship with mitral regurgitation better than conventional indicators used for LA geometry and function assessment. In patients with a moderate and pronounced degree of mitral regurgitation the deformation and deformation speed values are comparable, which demonstrates the significance of even moderate regurgitation for LA mechanical remodeling processes.

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