Vol. 27 No. 2 (2023): In focus: CardioOncology
REVIEWS

Technical aspects and outcomes of using homografts in atrioventricular valve surgery: a systematic review

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  • M.D. Nuzhdin,
  • R.N. Komarov,
  • D.A. Matsuganov,
  • I.Yu. Melnikov,
  • A.V. Tsaregorodtsev
M.D. Nuzhdin
Chelyabinsk Regional Clinical Hospital, Chelyabinsk
Bio
R.N. Komarov
Sechenov University, Moscow
D.A. Matsuganov
Chelyabinsk Regional Clinical Hospital, Chelyabinsk
I.Yu. Melnikov
Chelyabinsk Regional Clinical Hospital, Chelyabinsk
A.V. Tsaregorodtsev
Pirogov Russian National Research Medical University, Moscow
Identification of studies via databases
DOI: https://doi.org/10.21688/1681-3472-2023-2-42-53

Published 2023-06-30

Keywords

  • Allografts,
  • Mitral Valve,
  • Reoperation,
  • Tricuspid Valve

How to Cite

Nuzhdin, M., Komarov, R., Matsuganov, D., Melnikov, I., & Tsaregorodtsev, A. (2023). Technical aspects and outcomes of using homografts in atrioventricular valve surgery: a systematic review. Patologiya Krovoobrashcheniya I Kardiokhirurgiya, 27(2), 42–53. https://doi.org/10.21688/1681-3472-2023-2-42-53

Copyright (c) 2023 Nuzhdin M.D., Komarov R.N., Matsuganov D.A., Melnikov I.Yu., Tsaregorodtsev A.V.

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

Objective: To summarize and critically appraise the world experience with homografts in mitral and tricuspid valve surgery.
Methods: We conducted a systematic review according to the PRISMA criteria. We searched the following terms in available databases, such as PubMed (National Center for Biotechnology Information), Cochrane Library, Web of Science (Clarivate), and Google Scholar: ((mitral homograft) OR (tricuspid homograft) OR (homograft) AND (valve replacement) OR (valve repair)).
Results: We recruited 3 specialists to search the information matching our inclusion and exclusion criteria and selected 23 publications covering the period 1988-2021 for analysis. The mean follow-up period was 15 [6-60] months. Survival at the end of the follow-up period was 100% [90.7%-100.0%]; freedom from graft dysfunction was 100%, and freedom from reoperation was 100% [79%-100%].
Conclusion: The world experience with homografts in atrioventricular valve surgery is limited to small case series with inconclusive surgical aspects and a heterogeneous follow-up period. The immediate results suggest that homografts could be used as an alternative valve substitute for a wide spectrum of diseases both in primary and revision surgery.

Received 19 April 2023. Revised 14 May 2023. Accepted 15 May 2023.

Funding: The study did not have sponsorship.

Conflict of interest: The authors declare no conflict of interest.

Contribution of the authors
Conception and study design: M.D. Nuzhdin, R.N. Komarov
Data collection and analysis: M.D. Nuzhdin, D.A. Matsuganov, I.Yu. Melnikov, A.V. Tsaregorodtsev
Statistical analysis: D.A. Matsuganov
Drafting the article: M.D. Nuzhdin
Critical revision of the article: R.N. Komarov, M.D. Nuzhdin
Final approval of the version to be published: M.D. Nuzhdin, R.N. Komarov, D.A. Matsuganov, I.Yu. Melnikov, A.V. Tsaregorodtsev

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