Tolerance for physical activity and speckle tracking-characteristics of right ventricle deformation in young patients with connective tissue dysplasia
Published 2014-02-28
Keywords
- TOLERANCE,
- RIGHT VENTRICLE,
- DYSPLASIA,
- SPECKLE TRACKING
How to Cite
Copyright (c) 2014 Potapov V.V., Druk I.V., Nechaeva G.I., Smyalovskiy V.E., Kolmenkova I.V., Sidorova N.Yu.

This work is licensed under a Creative Commons Attribution 4.0 International License.
Abstract
In order to clarify the state of physical performance of young patients with signs of poorly differentiated connective tissue dysplasia (CTD) in comparison with morphometric and functional performance of the heart, an open comparative study was conducted. Speckle tracking (ST) echocardiography was applied for quantitative evaluation of deformation properties of the right ventricle (RV) free wall. The study included 549 patients with CTD (330 men, mean age 23.51±8.67). An average diagnostic coefficient of CTD was 28.84±10.76. The main symptoms were CTD changes in the musculoskeletal system (n = 549), cardiovascular system (n=409), skin (n=169) and respiratory system (n=119). 44 patients with CTD and low exercise tolerance and 13 healthy volunteers were tested by using a speckle tracking technique. In the group of patients with CTD a significantly higher incidence of low exercise tolerance and dystonic reactions to physical exertion were observed. Also recorded were changes in the ST-parameters of RV systolic strain.
References
- Нечаева Г., Викторова И., Друк И. // Врач. 2006. № 1. С. 19-23.
- Нечаева Г.И., Конев В.П. Викторова И.А. и др. // Рос. медицинские вести. 2004. № 3. С. 25-32.
- Рекомендации по количественной оценке структуры и функции камер сердца // Рос. кардиологический журнал. 2012. № 3 (95). Прил. 1. С. 1-28.
- Михайлов В.М. Нагрузочное тестирование под контролем ЭКГ: велоэргометрия, тредмил-тест, степ-тест, ходьба. Иваново, 2005.
- Rudski L., Lai W., Afilalo J. et al. // J. Am. Soc. Echocardiogr. 2010. V. 23. Р. 685-713.
- Яковлев В.М., Карпов Р.С., Швецова Е.В. Соединительнотканная дисплазия митрального клапана. Томск, 2004.
- Яковлев В.М., Нечаева Г.И. Кардиореспираторные синдромы при дисплазии соединительной ткани. Омск, 1994.
- Koumboerlis A.C. // Paediatric. Respiratory Reviews. 2009. V. 10. P. 3-6.
- Яковлев В.М., Нечаева Г.И., Бакулина Е.Г. Основы клинической диагностики дисплазии соединительной ткани: руководство для практического врача. Ставрополь, 2011.
- Mocchegiani R., Badano L., Lestuzzi Ch. et al. // Am. J. Card. 1995. V. 76. № 12. P. 941-946.
- Narayan R., Vaishnava P., Castellano J. et al. // J. Thorac. Cardiovasc. Surg. 2012. V. 143. P. 41-42.
- Хадзегова А. // Медицинский вестник. 2010. № 3. http://www.medvestnik.ru/articles/sovremennye_tehnologii_v_ ehokardiografii/
- Ermacora D., Badano L., Muraru D. et al. // Eur. Heart J. 2013. V. 34. P. 684.
- Gustafsson U., Lindqvist P. et al. // J. Am. Soc. Echocardiogr. 2008. V. 21. P. 1326-1330.
- Pettersen E., Helle-Valle Th., Edvardsen Th. et al. // J. Am. Coll. Cardiol. 2007. V. 49. P. 2450-2456.