Vol. 23 No. 4 (2019)
CASE REPORTS

Redo aortic root operations in late prosthetic endocarditis: clinical case series

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  • I. Skopin,
  • P. Kakhktsyan,
  • M. Latyshev,
  • D. Murysova,
  • T. Kupriy,
  • I. Zhangeriev,
  • E. Khasigova,
  • L. Enokyan
I. Skopin
A.N. Bakulev National Medical Research Center of Cardiovascular Surgery, Moscow
P. Kakhktsyan
A.N. Bakulev National Medical Research Center of Cardiovascular Surgery, Moscow,
M. Latyshev
A.N. Bakulev National Medical Research Center of Cardiovascular Surgery, Moscow
Bio
D. Murysova
A.N. Bakulev National Medical Research Center of Cardiovascular Surgery, Moscow
T. Kupriy
A.N. Bakulev National Medical Research Center of Cardiovascular Surgery, Moscow
I. Zhangeriev
A.N. Bakulev National Medical Research Center of Cardiovascular Surgery, Moscow
E. Khasigova
A.N. Bakulev National Medical Research Center of Cardiovascular Surgery, Moscow
L. Enokyan
A.N. Bakulev National Medical Research Center of Cardiovascular Surgery, Moscow
DOI: https://doi.org/10.21688/1681-3472-2019-4-73-82

Published 2019-12-27

Keywords

  • aortic root reconstruction,
  • aortic valve,
  • clinical case,
  • prosthetic infective endocarditis,
  • re-Bentall,
  • redo operations
    • ...More
    Less

How to Cite

Skopin, I., Kakhktsyan, P., Latyshev, M., Murysova, D., Kupriy, T., Zhangeriev, I., Khasigova, E., & Enokyan, L. (2019). Redo aortic root operations in late prosthetic endocarditis: clinical case series. Patologiya Krovoobrashcheniya I Kardiokhirurgiya, 23(4), 73–82. https://doi.org/10.21688/1681-3472-2019-4-73-82

Copyright (c) 2019 Skopin I. I., Kakhktsyan P. V., Latyshev M. S., Murysova D. V., Kupriy T. A., Zhangeriev I. A., Khasigova E. V., Enokyan L. Zh.

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

Prosthetic aortic valve endocarditis is a severe disease that quickly leads to heart failure. Owing to microorganisms and their toxins constantly entering the bloodstream, bypassing biological barriers, and hemodynamic disturbances, systemic embolism develops quite quickly, leading to sepsis and multi-organ failure. Conservative antibiotic therapy is often not effective because the infectious focus is located in the avascular zone. The presence of an implanted foreign body promotes adhesion of bacteria on the surface of the prosthetic tissue with simultaneous isolation from the action of phagocytes. Conservative treatment of prosthetic infectious endocarditis has an extremely unfavourable prognosis. Hospital mortality without operation is approximately 80%. Operations for prosthetic infectious endocarditis of the aortic valve are technically complex and require a highly qualified operating surgeon. The most difficult operations involve extension of the abscess to the aortic root, area of mitralaortic continuity and left ventricular outflow tract. In such situations, it is necessary to perform complex reconstructive operations on the aortic root, mitral-aortic continuity and left ventricular outflow tract. This study presents an overview of a series of complex redo operations on the aortic root and the ascending aorta in late prosthetic infectious endocarditis, with an analysis of the main tactical and technical aspects of the operations. Moreover, similar operations can be performed with good results by an experienced cardiac surgeon. In this case, it is necessary that prior to operation, the surgeon develops an algorithm of actions and determines 1) optimal access to the heart, 2) perfusion scheme, 3) type of implantable conduit, 4) cardiolysis performance features, 5) myocardial protection scheme and 6) features of the treatment of the infectious focus.

Received 29 October 2019. Revised 19 December 2019. Accepted 23 December 2019.

Funding: The study did not have sponsorship.

Conflict of interest: Authors declare no conflict of interest.

Author contributions
Drafting the article: I.I. Skopin, P.V. Kakhktsyan, M.S. Latyshev, D.V. Murysova, T.A. Kupriy, I.A. Zhangeriev
Critical revision of the article: I.I. Skopin, P.V. Kakhktsyan, M.S. Latyshev, D.V. Murysova, T.A. Kupriy, I.A. Zhangeriev, E.V. Khasigova, L.Zh. Enokyan
Surgical treatment I.I. Skopin, P.V. Kakhktsyan
Diagnostics: L.Zh. Enokyan
Treatment: D.V. Murysova, T.A. Kupriy
Assistance in surgery: M.S. Latyshev, E.V. Khasigova
Final approval of the version to be published: I.I. Skopin, P.V. Kakhktsyan, M.S. Latyshev, D.V. Murysova, T.A. Kupriy, I.A. Zhangeriev, E.V. Khasigova, L.Zh. Enokyan

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