Vol. 18 No. 2 (2014)
ANESTHESIOLOGY & RESUSCITATION

Characteristics of gram-negative microflora isolated from the blood of cardiac patients over 5 years

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  • L. Samoylova,
  • A. Shilova,
  • Yu. Gorbatykh,
  • S. Prokhorov,
  • O. Strunin,
  • M. Novikova
L. Samoylova
Academician Ye. Meshalkin Novosibirsk Research Institute of Circulation Pathology
Bio
A. Shilova
Academician Ye. Meshalkin Novosibirsk Research Institute of Circulation Pathology
Bio
Yu. Gorbatykh
Academician Ye. Meshalkin Novosibirsk Research Institute of Circulation Pathology
Bio
S. Prokhorov
Academician Ye. Meshalkin Novosibirsk Research Institute of Circulation Pathology
Bio
O. Strunin
Academician Ye. Meshalkin Novosibirsk Research Institute of Circulation Pathology
Bio
M. Novikova
Academician Ye. Meshalkin Novosibirsk Research Institute of Circulation Pathology
Bio
DOI: https://doi.org/10.21688/1681-3472-2014-2-49-54

Published 2014-06-10

Keywords

  • BACTEREMIA,
  • GRAM-NEGATIVE PATHOGENS,
  • RESISTANCE

How to Cite

Samoylova, L., Shilova, A., Gorbatykh, Y., Prokhorov, S., Strunin, O., & Novikova, M. (2014). Characteristics of gram-negative microflora isolated from the blood of cardiac patients over 5 years. Patologiya Krovoobrashcheniya I Kardiokhirurgiya, 18(2), 49–54. https://doi.org/10.21688/1681-3472-2014-2-49-54

Copyright (c) 2014 Samoylova L.M., Shilova A.N., Gorbatykh Yu.N., Prokhorov S.N., Strunin O.V., Novikova M.A.

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

Currently gram-negative bacteria are recognized as the most problematic pathogens. The authors studied the incidence of bacteremia caused by gram-negative microflora and its sensitivity to antibiotics in patients who underwent cardiac surgery. We analyzed the results of blood tests over a period of 5 years, from 2007 to 2011. During this period, 216 strains of gram-negative bacteria were identified. Enterobacteria accounted for 57.4% (124) of the structure of the gram-negative flora, while 42.6% (92) were glucose non-fermentative gram-negative bacteria. The prevailing pathogens detected when studying cardiac patients' blood were K. pneumoniae (25.5%) and P. aeruginosa (15.3%). The infections caused by K. pneumoniae are most efficiently treated by using carbapenems. As for P. aeruginosa, the most efficient antibiotics to fight this pathogen are piperacillin/tazobactam, amikacin, netilmicin. Carbapenems should be prescribed only after the sensitivity of microorganisms to these antibiotics is determined.

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