Published 2018-12-29
Keywords
- bioprosthesis,
- mitral valve,
- transcatheter mitral valve implantation
How to Cite
Copyright (c) 2018 Sharifulin R. M., Bogachev-Prokophiev A. V., Zhuravleva I. Yu., Timchenko T. P., Zykov I. S., Boyarkin E. V., Ovcharov M. A., Karaskov A. M.
This work is licensed under a Creative Commons Attribution 4.0 International License.
Abstract
Aim. The aim of the study was to evaluate a prototype of a delivery system for transcatheter mitral valve replacement in vitro and in laboratory animal implantation.
Methods. The prototypes of the delivery system and transcatheter mitral valve prosthesis were evaluated in vitro in an isolated pig heart using transapical access. In an experiment on a large laboratory animal implantation was performed using transatrial access.
Results. It was found out that the prototype of the delivery system allows to adequately deliver and release the transcatheter prosthesis in implantation zone using transatrial and transapical approaches without frame deformation and valve dysfunction.
Conclusion. The delivery system prototype for transcatheter mitral valve replacement demonstrated satisfactory characteristics during in vitro experiment and large laboratory animal implantation.
Received 26 November 2018. Revised 17 December 2018. Accepted 21 December 2018.
Funding: The study was carried out with the support of a grant of the Russian Science Foundation No. 16-15-10315.
Conflict of interest: Author declare no conflict of interest.
Author contributions
Conception and study design: I.Y. Zhuravleva
Data collection and analysis: T.P. Timchenko, M.A. Ovcharov, E.V. Boyarkin
Drafting the article: R.M. Sharifulin, I.S. Zykov
Critical revision of the article: A.V. Bogachev-Prokophiev, A.M. Karaskov
Final approval of the version to be published: R.M. Sharifulin, A.V. Bogachev-Prokophiev, I.Y. Zhuravleva, T.P. Timchenko, I.S. Zykov, E.V. Boyarkin, M.A. Ovcharov, A.M. Karaskov
References
- Журавлева И.Ю., Богачев-Прокофьев А.В., Демидов Д.П., Караськов А.М. Транскатетерное протезирование митрального клапана: современное состояние проблемы. Кардиология. 2017;57(8):51-9. http://dx.doi.org/10.18087/cardio.2017.8.10018 [Zhuravleva I.Y., Bogachev-Prokophiev A.V., Demidov D.P., Karaskov A.M. Transcatheter implantation of mitral valve prostheses: current status of the problem. Kardiologiia. 2017;57(8):51-9. (In Russ.) http://dx.doi.org/10.18087/cardio.2017.8.10018]
- Шарифулин Р.М., Богачев-Прокофьев А.В., Журавлева И.Ю., Тимченко Т.П., Железнев С.И., Караськов А.М. Результаты транскатетерного протезирования митрального клапана. Российский кардиологический журнал. 2018;23(11):137-144. https://doi.org/10.15829/1560-4071-2018-11-137-144 [Sharifulin R.M., Bogachev-Prokophiev A.V., Zhuravleva I.Y., Timchenko T.P., Zheleznev S.I., Karaskov A.M. Results of transcatheter mitral valve replacement. Russian Journal of Cardiology. 2018;23(11):137-144. (In Russ.) http://dx.doi.org/10.15829/1560-4071-2018-11-137-144]
- Regueiro A., Granada J.F., Dagenais F., Rodes-Cabau J. Transcatheter mitral valve replacement: insights from early clinical experience and future challenges. J Am Coll Cardiol. 2017;69:2175-92. PMID: 28449780. http://dx.doi.org/10.1016/j.jacc.2017.02.045
- Sorajja P., Maisano F. Percutaneous treatment for native mitral regurgitation. Progress in Cardiovascular Diseases. 2017;60(3):405-14. PMID: 29133070. http://dx.doi.org/10.1016/j.pcad.2017.11.003
- Журавлева И.Ю., Нуштаев Д.В., Тимченко Т.В., Требушат Д.В., Майоров А.П., Железнев С.И., Демидов Д.П., Богачев-Прокофьев А.В. Модель устройства для транскатетерной замены митрального биопротеза при его дисфункции. Cовременные технологии в медицине. 2017;9(3):7-14. http://dx.doi.org/10.17691/stm2017.9.3.0 [Zhuravleva I.Y., Nushtaev D.V., Timchenko T.V. Trebushat D.V., Mayorov A.P., Zheleznev S.I., Demidov D.P., Bogachev-Prokophiev A.V. The concept of a device for the redo transcatheter mitral valve implantation. Sovremennye Tehnologii v Medicine. 2017;9(3):7-14. (In Russ.) http://dx.doi.org/10.17691/stm2017.9.3.0]
- Богачев-Прокофьев А.В., Журавлева И.Ю., Шарифулин Р.М., Железнев С.И., Демидов Д.П., Кливер Е.Э., Караськов А.М. Имплантация in vitro первого отечественного транскатетерного протеза в нативный митральный клапан. Патология кровообращения и кардиохирургия. 2018;22(1):22-8. http://dx.doi.org/10.21688-1681-3472-2018-1-22-28 [Bogachev-Prokophiev A.V., Zhuravleva I.Yu, Sharifulin R.M., Zheleznev S.I., Demidov D.P., Kliver E.E., Karaskov A.M. In vivo implantation of a new transcatheter prosthesis in mitral valve position. Patologiya krovoobrashcheniya i kardiokhirurgiya = Circulation Pathology and Cardiac Surgery. 2018;22(1):22-8. (In Russ.) http://dx.doi.org/10.21688-1681-3472-2018-1-22-28]
- De Backer O., Piazza N., Banai S., Lutter G., Maisano F., Herrmann H.C., Franzen O.W., Søndergaard L. Percutaneous transcatheter mitral valve replacement: an overview of devices in preclinical and early clinical evaluation. Circ Cardiovasc Interv. 2014;7(3):400-9. PMID: 24944303. http://dx.doi.org/10.1161/CIRCINTERVENTIONS.114.001607
- Ussia G.P., Quadri A., Cammalleri V., De Vico P., Muscoli S., Marchei M., Ruvolo G., Sondergaard L., Romeo F. Percutaneous transfemoral-transseptal implantation of a second-generation CardiAQ mitral valve bioprosthesis: first procedure description and 30-day follow-up. EuroIntervention. 2016;11(10):1126-31. PMID: 26342591. http://dx.doi.org/10.4244/EIJY15M09_01
- Ussia G.P., Cammalleri V., Mehta J.L., Sarkar K., Muscoli S., de Vico P., Ruvolo G., Romeo F. Transcatheter mitral valve replacement with a novel self-expandable prosthesis: single institutional experience procedural outcomes and follow-up. J Cardiovasc Med (Hagerstown). 2017;18(6):415-4. PMID: 28240641. http://dx.doi.org/10.2459/JCM.0000000000000513