Vol. 16 No. 1 (2012)
ANESTHESIOLOGY, RESUSCITATION AND PERFUSIOLOGY

Efficacy of G-CSF mobilization CD34+ progenitor cells depending on ischemic history and age of patients with chronic heart failure

PDF (Русский)
  • I. Kim,
  • O. Poveshchenko,
  • V. Konenkov,
  • Ye. Pokushalov,
  • A. Romanov,
  • N. Bondarenko,
  • A. Poveshchenko,
  • D. Sergeevichev,
  • A. Karaskov
I. Kim
Research Institute of Clinical and Experimental Lymphology SB RAMS
Bio
O. Poveshchenko
Research Institute of Clinical and Experimental Lymphology SB RAMS
Bio
V. Konenkov
Research Institute of Clinical and Experimental Lymphology SB RAMS
Bio
Ye. Pokushalov
Academician E.N. Meshalkin Novosibirsk Research Institute of Circulation Pathology
Bio
A. Romanov
Academician E.N. Meshalkin Novosibirsk Research Institute of Circulation Pathology
Bio
N. Bondarenko
Research Institute of Clinical and Experimental Lymphology SB RAMS
Bio
A. Poveshchenko
Research Institute of Clinical and Experimental Lymphology SB RAMS
Bio
D. Sergeevichev
Academician E.N. Meshalkin Novosibirsk Research Institute of Circulation Pathology
Bio
A. Karaskov
Academician E.N. Meshalkin Novosibirsk Research Institute of Circulation Pathology
Bio
DOI: https://doi.org/10.21688/1681-3472-2012-1-75-78

Published 2012-03-28

Keywords

  • PROGENITOR CELLS,
  • G-CSF-MOBILIZATION,
  • CORONARY HEART DISEASE

How to Cite

Kim, I., Poveshchenko, O., Konenkov, V., Pokushalov, Y., Romanov, A., Bondarenko, N., Poveshchenko, A., Sergeevichev, D., & Karaskov, A. (2012). Efficacy of G-CSF mobilization CD34+ progenitor cells depending on ischemic history and age of patients with chronic heart failure. Patologiya Krovoobrashcheniya I Kardiokhirurgiya, 16(1), 75–78. https://doi.org/10.21688/1681-3472-2012-1-75-78

Copyright (c) 2012 Kim I.I., Poveshchenko O.V., Konenkov V.I., Pokushalov Ye.A., Romanov A.B., Bondarenko N.A., Poveshchenko A.F., Sergeevichev D.S., Karaskov A.M.

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

It is shown that administration of G-CSF (Granulocyte Colony Stimulating Factor) to patients with chronic heart failure has a gematologic effect, while increasing the number of leukocytes and neutrophils in the peripheral blood. G-CSF leads to mobilization of progenitor cells (PCs) from the bone marrow into the peripheral blood. The basal content of CD34+ cells, the number of heart attacks and the time period from the last myocardial infarction effect the number of CD34+ cells after mobilization.
PDF (Русский)

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