Vol. 21 No. 4 (2017)
ANGIOLOGY & VASCULAR SURGERY

Assessment of a diurnal blood pressure profile in patients with acute Lyme borreliosis

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  • A. Sandugei,
  • M. Ilyin,
  • O. Khrustalev,
  • N. Baranova,
  • N. Emanuilova,
  • O. Churakov,
  • V. Neusypin
A. Sandugei
Yaroslavl State Medical University, Ministry of Health of the Russian Federation, Yaroslavl, Russian Federation
M. Ilyin
Yaroslavl State Medical University, Ministry of Health of the Russian Federation, Yaroslavl, Russian Federation
O. Khrustalev
Yaroslavl State Medical University, Ministry of Health of the Russian Federation, Yaroslavl, Russian Federation
N. Baranova
Yaroslavl State Medical University, Ministry of Health of the Russian Federation, Yaroslavl, Russian Federation
N. Emanuilova
Yaroslavl State Medical University, Ministry of Health of the Russian Federation, Yaroslavl, Russian Federation
O. Churakov
Yaroslavl State Medical University, Ministry of Health of the Russian Federation, Yaroslavl, Russian Federation
V. Neusypin
Yaroslavl Regional Hospital No. 7, Yaroslavl, Russian Federation
Bio
DOI: https://doi.org/10.21688/1681-3472-2017-4-38-49

Published 2017-12-28

Keywords

  • Lyme disease,
  • hypertension,
  • hyperkinetic type of circulation,
  • daily blood pressure profile

How to Cite

Sandugei, A., Ilyin, M., Khrustalev, O., Baranova, N., Emanuilova, N., Churakov, O., & Neusypin, V. (2017). Assessment of a diurnal blood pressure profile in patients with acute Lyme borreliosis. Patologiya Krovoobrashcheniya I Kardiokhirurgiya, 21(4), 38–49. https://doi.org/10.21688/1681-3472-2017-4-38-49

Copyright (c) 2017 Sandugei A.V., Ilyin M.V., Khrustalev O.A., Baranova N.S., Emanuilova N.V., Churakov O.Yu., Neusypin V.V.

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

Aim. The purpose of the study was to investigate the character of changes in daily blood pressure profiles and to evaluate the influence of Borrelia burgdorferi infection on the course of essential hypertension in patients with acute stage of Lyme disease.
Methods. 37 patients with an acute stage of Lyme disease were examined and broken down in two groups. The first group included 18 patients without essential hypertension. 19 patients with stage II of essential hypertension were included into group II. The group of comparison consisted of 32 patients with stage II of essential hypertension without Lyme disease. 26 healthy volunteers of the control group were comparable in gender and age.
Results. A significant difference of the average diastolic blood pressure index during night time in patients with acute stage of Lyme disease and essential hypertension 90.0 (68.5–100.0) mm Hg versus the control group 77.0 (65.0–86.0) mm Hg at p = 0.03 was observed. When determining a type of daily blood pressure profile, some features of a blood pressure circadian rhythm were found in all groups of patients. There were ‘Dipper’ (77.7%) and ‘Non-Dipper’ (22.3%) profiles in the group of patients with acute stage of Lyme disease without essential hypertension. No ‘Over-Dipper’ and ‘Night-Peaker’ profiles were recorded in this group. 'Dipper’ (20.0%), ‘Non-Dipper’ (73.4%) and ‘Night-Peaker’ (6.6%) blood pressure profiles were typical for patients with acute stage of Lyme disease and essential hypertension.
Conclusion. A 22.3% decrease in the number of patients with a ‘Dipper’ blood pressure daily profile and an equal increase in the number of ‘non-dipper’ patients are characteristic of an acute stage of Lyme disease. The number of ‘Non-Dipper’ patients with essential hypertension and acute stage of Lyme disease increases up to 73.4%. Thus, acute Lyme disease and essential hypertension tend to burden the each other’s course.

Received 10 May 2017. Revised 7 September 2017. Accepted 25 September 2017.

Funding: The study did not have sponsorship.

Conflict of interest: Authors declare no conflict of interest.

Author contributions
Conception and study design: A.V. Sandugei, M.V. Ilyin, O.A. Khrustalev, N.S. Baranova.
Data collection and analysis: A.V. Sandugei, O.A. Khrustalev, N.V. Emanuilova.
Statistical data analysis: A.V. Sandugei, N.V. Emanuilova, O.Yu. Churakov.
Drafting the article: A.V. Sandugei, N.V. Emanuilova, V.V. Neusypin.
Critical revision of the article: A.V. Sandugei, N.V. Emanuilova, V.V. Neusypin.
Final approval of the version to be published: A.V. Sandugei, M.V. Ilyin, O.A. Khrustalev, N.S. Baranova, N.V. Emanuilova, O.Yu. Churakov, V.V. Neusypin

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