Vol. 18 No. 3 (2014): Cardioanesthesiology (Special Issue)
REVIEWS

Persistent multiorgan failure

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  • Ye. Grigorev,
  • G. Plotnikov,
  • D. Shukevich,
  • A. Golovkin
Ye. Grigorev
Scientific Research Institute for Complex Issues of Cardiovascular Diseases
Bio
G. Plotnikov
Scientific Research Institute for Complex Issues of Cardiovascular Diseases
Bio
D. Shukevich
Scientific Research Institute for Complex Issues of Cardiovascular Diseases
Bio
A. Golovkin
Scientific Research Institute for Complex Issues of Cardiovascular Diseases
Bio
DOI: https://doi.org/10.21688/1681-3472-2014-3-82-86

Published 2014-07-15

Keywords

  • SYSTEMIC INFLAMMATORY RESPONSE,
  • PERSISTENT INFLAMMATION,
  • IMMUNE SUPPRESSION,
  • EXTREME MYELOPOIESIS,
  • AUTOPHAGY

How to Cite

Grigorev, Y., Plotnikov, G., Shukevich, D., & Golovkin, A. (2014). Persistent multiorgan failure. Patologiya Krovoobrashcheniya I Kardiokhirurgiya, 18(3), 82–86. https://doi.org/10.21688/1681-3472-2014-3-82-86

Copyright (c) 2014 Grigorev Ye.V., Plotnikov G.P., Shukevich D.L., Golovkin A.S.

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

Persistent multiple organ failure is a topical and relatively common problem in critically ill patients. We summarize the pathophysiological characteristics of this syndrome, namely the ratio of pro-and antiinflammatory components of the systemic inflammatory response, the formation of immune suppression and catabolism, pathological myelopoiesis, autophagy. The clinical and laboratory characteristics of probable diagnostics and the principal directions of intensive therapy are given.
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References

  1. Moore F.A., Moore E.E. // Surg. Clin. North Am. 1995. V. 75 (2). P. 257-277.
  2. Moore F.A. // Am. J. Surg. 1999. V. 178 (6). P. 449-453.
  3. Fukushima R., Alexander J.W., Gianotti L. et al. // Shock. 1995. V. 3 (5). P. 323-328.
  4. Shoemaker W., Appel P., Kram H. // Crit. Care Med. 1988. V. 16 (11). Р. 1117-1120.
  5. Matzinger P. // Science. 2002. V. 296. P. 301-305.
  6. Zhang Q., Raoof M., Chen Y. et al. // Nature. 2010. V. 464. P. 104-107.
  7. Moore F.A., Sauaia A., Moore E. et al. // J. Trauma. 1996. V. 40 (4). P. 501-510.
  8. Ciesla D.J., Moore E.E., Johnson J. et al. // Arch. Surg. 2005. V. 140 (5). P. 432-438.
  9. Hotchkiss R., Opal S. // N. Engl. J. Med. 2010. V. 363 (1). P. 87-89.
  10. Kawai T., Akira S. // Nat. Immunol. 2010. V. 11 (5). P. 373-384.
  11. Kawai T., Akira S. // Trends Mol. Med. 2007. V. 13 (11). P. 460-469.
  12. Hotchkiss R., Coopersmith C., McDunn J., Ferguson T. // Nat. Med. 2009. V. 15 (5). P. 496-497.
  13. Wiersinga W. // Curr. Opin. Crit. Care. 2011. V. 17 (5). P. 480-486.
  14. Oberholzer A., Oberholzer C., Moldawer L. // Shock. 2001. V. 16 (2). P. 83-96.
  15. Eichacker P.Q., Parent C., Kalil A. et al. // Am. J. Respir. Crit. Care Med. 2002. V. 166 (9). P. 1197-1205.
  16. Xiao W., Mindrinos M.N., Seok J. et al. // J. Exp. Med. 2011. V. 208 (13). P. 2581-2590.
  17. Qiu P., Cui X., Barochia A. et al. // Expert Opin Investig Drugs. 2011. V. 20 (11). P. 1555-1564.
  18. Bone R.C. // Crit. Care Med. 1996. V. 24 (1). P. 163-172.
  19. Moldawer L.L. // Blood Purif. 1993. V. 11 (2). P. 128-133.
  20. Osuchowski M., Welch K., Siddiqui J., Remick D. // J. Immunol. 2006. V. 177 (3). P. 1967-1974.
  21. Xiao W., Mindrinos M.N., Seok J. et al. // J. Exp. Med. 2011. V. 208 (13). P. 2581-2590.
  22. Monneret G., Lepape A., Voirin N. et al. // Intensive Care Med. 2006. V. 32 (8). P. 1175-1183.
  23. Nierhaus A., Montag B., Timmler N. et al. // Intensive Care Med. 2003. V. 29 (4). P. 646-651.
  24. Docke W.D., Randow F., Syrbe U. et al. // Nat. Med. 1997. V. 3 (6). P. 678-681.
  25. Kelly-Scumpia K., Scumpia P., Delano M. et al. // J. Exp. Med. 2010. V. 207 (2). P. 319-326.
  26. Boomer J., To K., Chang K. et al. // JAMA. 2011. V. 306 (23). P. 2594-2605.
  27. Inoue S., Bo L., Bian J. et al. // Shock. 2011. V. 36 (1). P. 38-44.
  28. Hotchkiss R.S., Karl I.E. // N. Engl. J. Med. 2003. V. 348 (2). P. 138-150. хелперов [26-28].
  29. Said E., Dupuy F., Trautmann L. et al. // Nat. Med. 2010. V. 16 (4). P. 452-459.
  30. Inoue S., Unsinger J., Davis C. et al. // J. Immunol. 2010. V. 184 (3). P. 1401-1409.
  31. Fehervari Z., Sakaguchi S. // J. Clin. Invest. 2004. V. 114 (9). P. 1209-1217.
  32. Scumpia P.O., Delano M.J., Kelly K.M. et al. // J. Immunol. 2006. V. 177 (11). P. 7943-7949.
  33. Scumpia P., Kelly-Scumpia K., Delano M. et al. // J. Immunol. 2010. V. 184 (5). P. 2247-2251.
  34. Cuenca A., Delano M., Kelly-Scumpia K. et al. // Mol. Med. 2011. V. 17 (3-4). P. 281-292. 35].
  35. Gabrilovich D.I., Nagaraj S. // Nat. Rev. Immunol. 2009. V. 9 (3). P. 162-174.
  36. Noel G., Wang Q., Schwemberger S. et al. // Shock. 2011. V. 36 (2). P. 149-155.
  37. Brealey D., Brand M., Hargreaves I. et al. // Lancet. 2002. V. 360. P. 219-223.
  38. Brealey D., Karyampudi S., Jacques T.S. et al. // Am. J. Physiol. Regul. Integr. Comp. Physiol. 2004. V. 286. P. R491-R497.
  39. Vanhorebeek I., De Vos R., Mesotten D. et al. // Lancet. 2005. V. 365. P. 53-59.
  40. Vanhorebeek I., Ellger B., De Vos R. et al. // Crit. Care Med. 2009. V. 37. P. 1355-1364.
  41. He C., Klionsky D.J. // Ann. Rev. Genet. 2009. V. 43. P. 67-93.
  42. Hsieh C.H., Pai P.Y., Hsueh H.W. et al. // Ann. Surg. 2011. V. 253. P. 1190-1200.
  43. Montejo J.C., Zarazaga A., Lopez-Martinez J. et al. // Clin. Nutr. 2003. V. 22. Р. 221-233.
  44. Spruijt N.E. et al. // Critical Care. 2010. V. 14. P. R150.