Vol. 21 No. 4 (2017)
REVIEWS

Using adenosine triphosphate in catheter radiofrequency pulmonary vein isolation: does elimination of “dormant” atriovenous conduction really allow to refine long-term results?

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  • Y. Krivosheev,
  • D. Bashta,
  • A. Simonyan,
  • T. Myznikova,
  • Z. Mishodzheva,
  • V. Kolesnikov
Y. Krivosheev
Stavropol Regional Cardiology Hospital, Stavropol, Russian Federation
Bio
D. Bashta
Stavropol Regional Cardiology Hospital, Stavropol, Russian Federation
A. Simonyan
Stavropol Regional Cardiology Hospital, Stavropol, Russian Federation
T. Myznikova
Stavropol Regional Cardiology Hospital, Stavropol, Russian Federation
Z. Mishodzheva
Stavropol Regional Cardiology Hospital, Stavropol, Russian Federation
V. Kolesnikov
Stavropol Regional Cardiology Hospital, Stavropol, Russian Federation
DOI: https://doi.org/10.21688/1681-3472-2017-4-23-30

Published 2017-12-28

Keywords

  • atrial fibrillation,
  • radiofrequency ablation,
  • adenosine triphosphate,
  • “dormant” atriovenous conduction

How to Cite

Krivosheev, Y., Bashta, D., Simonyan, A., Myznikova, T., Mishodzheva, Z., & Kolesnikov, V. (2017). Using adenosine triphosphate in catheter radiofrequency pulmonary vein isolation: does elimination of “dormant” atriovenous conduction really allow to refine long-term results?. Patologiya Krovoobrashcheniya I Kardiokhirurgiya, 21(4), 23–30. https://doi.org/10.21688/1681-3472-2017-4-23-30

Copyright (c) 2017 Krivosheev Y.S., Bashta D.I., Simonyan A.A., Myznikova T.A., Mishodzheva Z.A., Kolesnikov V.N.

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

This literature review looks at the efficacy of removing “dormant” atriovenous conduction, which can be identified by means of intravenous ejection of adenosine triphosphate following catheter isolation of pulmonary vein ostia in patients with atrial fibrillation. The incidence of detecting conduction “breakthroughs” in the ablation lines when carrying out drug tests after isolation of pulmonary veins, as well as the prognostic significance of this phenomenon for atrial fibrillation recurrence are evaluated. Also assessed are drawbacks and limitations of the studies looking at the possibility of improving the efficiency of catheter ablation of atrial fibrillation by combining the removal of “dormant” atriovenous conduction zones identified by adenosine triphosphate testing and the ablation of ganglionated plexi.

Received 10 April 2017. Accepted 23 October 2017.

Funding: The study did not have sponsorship.

Conflict of interest: Authors declare no conflict of interest.

Author contributions
Conception and study design: Y.S. Krivosheev, V.N. Kolesnikov.
Data collection and analysis: Y.S. Krivosheev, D.I. Bashta.
Drafting the article: Y.S. Krivosheev, A.A. Simonyan.
Critical revision of the article: V.N. Kolesnikov.
Final approval of the version to be published: Y.S. Krivosheev, D.I. Bashta, A.A. Simonyan, T.A. Myznikova, Z.A. Mishodzheva, V.N. Kolesnikov.

 

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References

  1. Calkins H., Kuck K.H., Cappato R., Brugada J., Camm A.J., Chen S.A., Crijns H.J., Damiano R.J., Davies D.W., DiMarco J., Edgerton J., Ellenbogen K., Ezekowitz M.D., Haines D.E., Haissaguerre M., Hindricks G., Iesaka Y., Jackman W., Jalife J., Jais P., Kalman J., Keane D., Kim Y.H., Kirchhof P., Klein G., Kottkamp H., Kumagai K., Lindsay B.D., Mansour M., Marchlinski F.E., McCarthy P.M., Mont J.L., Morady F., Nademanee K., Nakagawa H., Natale A., Nattel S., Packer D.L., Pappone C., Prystowsky E., Raviele A., Reddy V., Ruskin J.N., Shemin R.J., Tsao H.M., Wilber D. 2012 HRS/EHRA/ECAS expert consensus statement on catheter and surgical ablation of atrial fibrillation: recommendations for patient selection, procedural techniques, patient management and follow-up, definitions, endpoints, and research trial design: a report of the Heart Rhythm Society (HRS) Task Force on Catheter and Surgical Ablation of Atrial Fibrillation. Developed in partnership with the European Heart Rhythm Association (EHRA), a registered branch of the European Society of Cardiology (ESC) and the European Cardiac Arrhythmia Society (ECAS); and in collaboration with the American College of Cardiology (ACC), American Heart Association (AHA), the Asia Pacific Heart Rhythm Society (APHRS), and the Society of Thoracic Surgeons (STS). Endorsed by the governing bodies of the American College of Cardiology Foundation, the American Heart Association, the European Cardiac Arrhythmia Society, the European Heart Rhythm Association, the Society of Thoracic Surgeons, the Asia Pacific Heart Rhythm Society, and the Heart Rhythm Society. Heart Rhythm. 2012;9(4):632-96. PMID: 22386883. https://doi.org/10.1016/j.hrthm.2011.12.016
  2. Haïssaguerre M., Jaimlis P., Shah D.C., Takahashi A., Hocini M., Quiniou G., Garrigue S., Le Mouroux A., Le Métayer P, Clémenty J. Spontaneous initiation of atrial fibrillation by ectopic beats originating in the pulmonary veins. N Engl J Med. 1998;339(10):659-66. PMID: 9725923. https://doi.org/10.1056/NEJM199809033391003
  3. Ouyang F., Tilz R., Chun J., Schmidt B., Wissner E., Zerm T., Neven K., Kokturk B., Konstantinidou M., Metzner A., Fuernkranz A., Kuck K.H. Long-term results of catheter ablation in paroxysmal atrial fibrillation: Lessons from a 5-year follow-up. Circulation. 2010;122(23):2368-77. PMID: 21098450. https://doi.org/10.1161/110.946806
  4. Cappato R., Negroni S., Pecora D., Bentivegna S., Lupo P.P., Carolei A., Es-posito C., Furlanello F., De Ambroggi L. Prospective assessment of late conduction recurrence across radiofrequency lesions producing electrical disconnection at the pulmonary vein ostium in patients with atrial fibrillation. Circulation. 2003;108(13):1599-604. PMID: 12963643. https://doi.org/10.1161/01.CIR.0000091081.19465.F1
  5. Arentz T., Macle L., Klaushe D. Hocini M., Jais P., Shan D., Haïssaguerre M. “Dormant” pulmonary vein conduction revealed by adenosine after ostial radiofrequency catheter ablation. J Cardiovasc Electrophysiol. 2004;15(9):1041-7. PMID: 15363077. https://doi.org/10.1046/j.1540-8167.2004.04031.x
  6. Tritto M., De Ponti R., Salerno-Uriarte J. Spadacini G., Marazzi R., Moretti P., Lanzotti M. Adenosine restores atriovenous conduction after apparently successful ostial isolation of the pulmonary veins. European Heart J. 2004;25(23):2155-63. PMID: 15571832. https://doi.org/10.1016/j.ehj.2004.08.023
  7. Matsuo S., Yamane T., Date T. Inada K., Kanzaki Ya., Tokuda M., Shibayama K., Miyanaga S., Miyazaki H., Sugimoto K., Mochizuki S. Reduction of AF recurrence after pulmonary vein isolation by eliminating ATP-induced transient venous re-conduction. J Cardiovasc Electrophysiol. 2007;18(7):704-8. PMID: 17506857. https://doi.org/10.1111/j.1540-8167.2007.00842.x
  8. Hachiya H., Hirao K., Takahashi A., Nagata Y., Suzuki K., Maeda S., Sasaki T., Kawabata M., Isobe M., Iesaka Y. Clinical implications of reconnection between the left atrium and isolated pulmonary veins provoked by adenosine triphosphate after extensive encircling pulmonary vein isolation. J Cardiovasc Electrophysiol. 2007;18(4):392-8. PMID: 17286569. https://doi.org/10.1111/j.1540-8167.2006.00753.x
  9. Gula L.J., Massel D., Leong-Sit P., Gray C., Fox D.J., Segal O.R., Krahn A.D., Yee R., Klein G.J., Skanes A.C. Does adenosine response predict clinical recurrence of atrial fibrillation after pulmonary vein isolation? J Cardiovasc Electrophysiol. 2011;22(9):982-6. PMID: 21371161. https://doi.org/10.1111/j.1540-8167.2011.02037.x
  10. Miyazaki S., Kuwahara T., Kobori A., Takahashi Y., Takei A., Sato A., Isobe M., Takahashi A. Impact of adenosine-provoked acute dormant pulmonary vein conduction on recurrence of atrial fibrillation. J Cardiovasc Electrophysiol. 2012;23(3):256-60. PMID: 22034876. https://doi.org/10.1111/j.1540-8167.2011.02195.x
  11. Matsuo S, Yamane T., Date T., Hioki M., Ito K., Narui R., Tanigawa S., Nakane T., Hama Y., Tokuda M., Yamashita S., Aramaki Y., Inada K., Shibayama K., Miyanaga S., Yoshida H., Miyazaki H., Abe K., Sugimoto K., Taniguchi I., Yoshimura M. Comparison of the clinical outcome after pulmonary vein isolation based on the appearance of adenosine-induced dormant pulmonary vein conduction. Am Heart J. 2010;160(2):337-45. PMID: 20691841. https://doi.org/10.1016/j.ahj.2010.05.025
  12. Cheung J.W., Lin F.S., Ip J.E., Bender S.R., Siddiqi F.K., Liu C.F., Thomas G., Markowitz S.M., Lerman B.B. Adenosine-induced pulmonary vein ectopy as a predictor of recurrent atrial fibrillation after pulmonary vein isolation. Circ Arrhythm Electrophysiol. 2013;6(6):1066-73. PMID: 24243786. https://doi.org/10.1161/CIRCEP.113.000796
  13. McLellan A.J.A., Kumar S., Smith C., Morton J., Kalmar J.M., Kistler P. The role of adenosine following pulmonary vein isolation in patients undergoing catheter ablation for atrial fibrillation. J Cardiovasc Electrophysiol. 2013;24(7):742-51. PMID: 23489944. https://doi.org/10.1111/jce.12121
  14. Lin F.S., Ip J.E., Markowitz S.M., Liu C.F., Thomas G., Lerman B.B., Cheung J.W. Limitations of dormant conduction as a predictor of atrial fibrillation recurrence and pulmonary vein reconnection after catheter ablation. Pacing Clin Electrophysiol. 2015;38(5):598-607. PMID: 25644741. https://doi.org/10.1111/pace.12596
  15. Лян Е.В. Рецидивы атрио-венозного проведения и течение фибрилляции предсердий после катетерной изоляции легочных вен. Дис. … канд. мед. наук. СПб, 2015. 138 с. [Lyan E.V. Recurence atrio-venous conduction and atrial fibrillation progression after pulmonary veins catheter isolation [dissertation]. Saint Petersburg, 2015. 138 p. (In Russ.)]
  16. Macle L., Khairy P., Weerasooriya R., Novak P., Verma A., Willems S., Arentz T., Deisenhofer I., Veenhuyzen G., Scavée C., Jaïs P., Puererfellner H., Levesque S., Andrade J.G., Rivard L., Guerra P.G., Dubuc M., Thibault B., Talajic M., Roy D., Nattel S. Adenosine-guided pulmonary vein isolation for the treatment of paroxysmal atrial fibrillation: an international, multicentre, randomised superiority trial. Lancet. 2015;386(9994):672-9. PMID: 26211828. https://doi.org/10.1016/S0140-6736(15)60026-5
  17. Kobori A, Shizuta S., Inoue K., Kaitani K., Morimoto T., Nakazawa Y., Ozawa T., Kurotobi T., Morishima I., Miura F., WatanabeT., Masuda M., Naito M., Fujimoto H., Nishida T., Furukawa Y., Shirayama T., Tanaka M., Okajima K., Yao T., Egami Y., Satomi K., Noda T., Miyamoto K., Haruna T., Kawaj T., Yoshizawa T., Toyota T., Yahata M., Nakai K., Sugiyama H., Higashi Y., It M., Horie M.I., Kusano K.F., Shimizu W., Kamakura S., Kimura T. Adenosine triphosphate-guided pulmonary vein isolation for atrial fibrillation: the UNmasking Dormant Electrical Reconduction by Adenosine TriPhosphate (UNDER-ATP) trial. Eur Heart J. 2015;36(46):3276-87. PMID: 26321237. https://doi.org/10.1093/eurheartj/ehv457
  18. Compier M.G., De Riva M., Dyrda K., Zeppenfeld K., Schalij M.J., Trines S.A. Incidence and predictors of dormant conduction after cryoballoon ablation incorporating a 30-min waiting period. Europace. 2015;17(12):1383-90. PMID: 25935164. https://doi.org/10.1093/europace/euu411
  19. Kumar N., Dinh T., Phan K., Timmermans C., Philippens S., Dassen W., Vranken N., Pison L., Maessen J., Crijns H.J. Adenosine testing after second-generation cryoballoon ablation (ATSCA) study improves clinical success rate for atrial fibrillation. J Interv Card Electrophysiol. 2014;41(1):91-7. PMID: 25972302. https://doi.org/10.1007/s10840-014-9921-z
  20. Miyazaki S., Taniguchi H., Nakamura H., Hachiya H., Ichihara N., Araki M., Kuroi A., Takagi T., Iwasawa J., Hirao K., Iesaka Y. Adenosine triphosphate test after cryothermal pulmonary vein isolation: creating contiguous lesions is essential for eliminating dormant conduction. J Cardiovasc Electrophysiol. 2015;26(10):1069-74. PMID: 26076357. https://doi.org/10.1111/jce.12726
  21. Callans D., Gerstenfeld E., Dixit S., Zado E., Vanderhoff M., Ren J., Marchlinski F. Efficacy of repeat pulmonary vein isolation procedures in patients with recurrent atrial fibrillation. J Cardiovasc Electrophysiol. 2004;15(9):1050-5. PMID: 15363079. https://doi.org/10.1046/j.1540-8167.2004.04052.x
  22. Nanthakumar K., Plumb V., Epstein A., Veenhuyzen G., Link D., Kay G. Resumption of electrical conduction in previously isolated pulmonary veins: Rationale for a different strategy? Circulation. 2004;109(10):1226-9. PMID: 14993124. https://doi.org/10.1161/01.CIR.0000121423.78120.49
  23. Lin W.S., Tai C.T., Hsieh M.H., Tsai C.F., Lin Y.K., Tsao H.M., Huang J.L., Yu W.C., Yang S.P., Ding Y.A., Chang M.S., Chen S.A. Catheter ablation of paroxysmal atrial fibrillation initiated by non-pulmonary vein ectopy. Circulation. 2003;107(25):3176-83. https://doi.org/10.1161/01.CIR.0000074206.52056.2D
  24. Elayi C.S., Di Biase L., Bai R., Burkhardt J.D., Mohanty P., Santangeli P., Sanchez J., Hongo R., Gallinghouse G.J., Horton R., Bailey S., Beheiry S., Natale A. Administration of isoproterenol and adenosine to guide supplemental ablation after pulmonary vein antrum isolation. J Cardiovasc Electrophysiol. 2013;24(11):1199-206. PMID: 24020649. https://doi.org/10.1111/jce.12252
  25. Cheng H., Dai Y.Y., Jiang R.H., Liu Q., Sun Y.X., Lin J.W., Zhang Z.W., Chen S.Q., Zhu J., Sheng X., Jiang C.Y. Non-pulmonary vein foci induced before and after pulmonary vein isolation in patients undergoing ablation therapy for paroxysmal atrial fibrillation: incidence and clinical outcome. J Zhejiang Univ-Sci B (Biomed & Biotechnol). 2014;15(10):915-22. PMCID: PMC4201320. https://doi.org/10.1631/jzus.B1400146