Mid-term results of mitral valve reconstruction by using D-ring and C-flex systems in patients with degenerative mitral valve disease
Published 2015-10-22
Keywords
- mitral insufficiency,
- mitral regurgitation,
- mitral valve repair,
- degenerative mitral valve disease
How to Cite
Copyright (c) 2015 Zheleznev S.I., Bogachev-Prokofiev A.V., Afanasyev A.V., Nazarov V.M., Demin I.I., Karaskov A.M.

This work is licensed under a Creative Commons Attribution 4.0 International License.
Abstract
Objective. The purpose of the research was to compare early and mid-term results following mitral valve repair by using semirigid and flexible annuloplasty rings.
Methods. Over a period from September 2011 to September 2014 171 patients with isolated mitral valve insufficiency were recruited and divided in two groups. Mean age in Group I (D-ring) was 57 years (42 to 65), while in group II (C flex) it was 54 years (41 to 63) (р = 0.092). Males constituted more than a half of patients in both groups (69% and 67% respectively).
Results. No early deaths (90 days) were registered. There were 4 transient ischemic attacks in group I (p = 0.042). At midterm follow up (24 months) the survival rate in D-ring and C flex groups accounted for 96.0±2.3% (95% CI 88.6-98.7%) and 94.3±2.8% (95% CI 85.5-97.9%) respectively (log-rank test = 0.899); freedom from reoperation ran to 97.0±2.1% (95% CI 88.4-99.3%) and 100% respectively (log-rank test = 0.044); freedom from significant recurrent mitral regurgitation came to 80.8±6.5% (95% CI 64.0-90.3%) and 92.8±3.1% (95% CI 83.4-97.0%) respectively (log-rank test = 0.002).
Conclusion. Using flexible C rings reduces the incidence of postoperative complications and provides better clinical and functional mid-term results as compared to semi-rigid annuloplasty rings in patients with severe mitral regurgitation due to degenerative mitral valve disease.
References
- Lillehei C.W., Gott V.L., Dewall R.A., Varco R.L. Surgical correction of pure mitral insufficiency by annuloplasty under direct vision // Lancet. 1957. Vol. 77. P. 446–449.
- Filsoufi F., Carpentier A. Principles of reconstructive surgery in degenerative mitral valve disease // Sem. Thorac. Cardiovasc. Surg. 2007. Vol. 19. № 2. P. 103–10. doi:10.1053/j.semtcvs.2007.04.003
- Brown M.L., Schaff H.V., Li Z., Suri R.M., et al. Results of mitral valve annuloplasty with a standard-sized posterior band: Is measuring important? // J. Thorac. Cardiovasc. Surg. 2009. Vol. 138. P. 886–91.
- Cosgrove D.M., Arcidi J.M., Rodriguez L., Stewart W.J., Powell K., Thomas J.D. Initial experience with the Cosgrove-Edwards annuloplasty system // Ann. Thorac. Surg. 1995. Vol. 60. P. 499–503.
- Lange R., Guenther T., Kiefer B., Noebauer C., Goetz W. et al. Mitral valve repair with the new semirigid partial Colvin–Galloway Future annuloplasty band // J. Thorac. Cardiovasc. Surg. 2008. Vol. 135. P. 1087–93.
- Назаров В.М., Железнев С.И., Желтовский Ю.В. и др. Коррекция митральной недостаточности с помощью опорных колец при дисплазии соединительной ткани // Сибирский медициинский журнал. 2013. № 8. С. 31–38.
- Богачев-Прокофьев А.В., Железнев С.И., Пивкин А.Н. и др. Сравнение биатриальной и левопредсердной процедуры радиочастотной аблации при коррекции клапанных пороков // Патология кровообращения и кардиохирургия. 2013. № 2. С. 12–16.
- Богачев-Прокофьев А.В., Железнев С.И., Пивкин А.Н. и др. Сравнение результатов конкомитантной процедуры MAZE III и радиочастотной аблации предсердий у пациентов с клапанными пороками сердца // Патология кровообращения и кардиохирургия. 2012. № 4. С. 9–14.
- Богачев-Прокофьев А.В., Железнев С.И., Пивкин А.Н. и др. Влияет ли тип аблационного устройства на результаты лечения фибрилляции предсердий при операциях на открытом сердце? // Патология кровообращения и кардиохирургия. 2013. № 2. С. 17–21.
- Железнев С.И., Богачев-Прокофьев А.В., Назаров В.М. и др. Отдаленные результаты хирургической процедуры maze у пациентов с клапанной патологией и фибрилляцией предсердий // Патология кровообращения и кардиохирургия. 2011. № 3. С. 17–21.
- Adams D.H., Rosenhek R., Falk V. Degenerative mitral valve regurgitation: best practice revolution // Eur. Heart J. 2010. Vol. 31. P. 1958–1967.
- Carpentier A. Cardiac valve surgery – the ‘‘French correction.’’ // J. Thorac. Cardiovasc. Surg. 1983. Vol. 863. P. 23–37.
- Varghese R., Anyanwu A.C., Itagaki S., Milla F., Castillo J., Adams D.H. Management of systolic anterior motion after mitral valve repair : An algorithm // J. Thorac. Cardiovasc. Surg. 2012. Vol. 143. № 4. P. S2–S7. doi:10.1016/j.jtcvs.2012.01.063
- Brown M.L., Abel M.D., Click R.L., Morford R.G., Dearani J.A., Sundt T.M., et al. Systolic anterior motion after mitral valve repair: is surgical intervention necessary? // J. Thorac. Cardiovasc. Surg. 2007. Vol. 133. P. 136–43.
- Filsoufi F., Carpentier A. Systolic anterior motion of the mitral valve // J. Thorac. Cardiovasc. Surg. 2007. Vol. 134. № 1. P. 265–266.
- Quigley R.L. Prevention of systolic anterior motion after repair of the severely myxomatous mitral valve with an anterior leaflet valvuloplasty // Ann. Thorac. Surg. 2005. Vol. 80. № 1. P. 179–182.
- Zegi R., Carpentier A., Doguet F., et al. Systolic anterior motion after mitral valve repair: an exceptional cause of late failure // J. Thorac. Cardiovasc. Surg. 2005. Vol. 130. № 5. P. 1453–1454.
- David T.E., Komeda M., Pollick C. et al. Mitral valve annuloplasty: the effect of the type on left ventricular function // Ann. Thorac. Surg. 1989. Vol. 47. P. 524–527.
- Jensen M.O., Jensen H., Smerup M., Levine R.A., Yoganathan A.P., Nygaard H. et al. Saddle-shaped mitral valve annuloplasty rings experience lower forces compared with flat rings // Circulation. 2008. Vol. 118. P. s250–s255.
- Jimenez J.H., Liou S.W., Padala M., He Z., Sacks M., Gorman R.C. et al. A saddle-shaped annulus reduces systolic strain on the central region of the mitral anterior leaflet // J. Thorac. Cardiovasc. Surg. 2007. Vol. 134. P. 1562–8.
- Ryan L.P., Jackson B.M., Hamamoto H., Eperjesi T.J., Plappert T.J., St.John M. et al. The influence of a annuloplasty geometry on mitral leaflet curvature // Ann. Thorac. Surg. 2008. Vol. 86. P. 749–60.
- Salgo I.S., Gorman J.H.III, Gorman R.C., Jackson B.M., Bowen F.M., Plappert T. et all. Effect of annular shape on leaflet curvature in reducing mitral leaflet stress // Circulation. 2002. Vol. 107. P. 711–7.
- Chang B.C., Youn Y.N., Ha J.W. et al. Long-term clinical results of mitral valvuloplasty using flexible and rigid rings: a prospective and randomized study // J. Thorac. Cardiovasc. Surg. 2007. Vol. 133. P. 995–1003.
- Carpentier A., Chauvaud S., Fabiani J.N., Deloche A., Relland J., Lessana A., et al. Reconstructive surgery of mitral valve incompetence: ten-year appraisal // J. Thorac. Cardiovasc. Surg. 1980. Vol. 79. P. 338–348.
- Flameng W., Meuris B., Herijgers P., Herregods M. Durability of mitral valve repair in Barlow disease versus fibroelastic deficiency // J. Thorac. Cardiovasc. Surg. 2008. Vol. 135. P. 274–282.
- Gillinov A.M., Cosgrove D.M. Mitral valve repair for degenerative disease // J. Heart Valve Dis. 2002. Vol. 11 (Suppl 1). P. S15–20.
- Gillinov A.M., Cosgrove D.M., Blackstone E.H. et al. Durability of mitral valve repair for degenerative disease // J. Thorac. Cardiovasc. Surg. 1998. Vol. 116. P. 737–743.
- Marwick T.H., Stewart W.J., Currie P.J., Cosgrove D.M. Mechanism of failure of mitral valve repair: an echocardiographic study // Am. Heart J. 1991. Vol. 122. P. 149–156.
- Mothy D., Orszulak T.A., Schaff H.V. Very long-term survival and durability of mitral valve repair for mitral valve prolapse //Circulation. 2001. Vol. 104 (Suppl 1). P. 1–7.
- Tesler U.F., Lanzillo G., Cerin G. Feasibility of mitral valve repair for degenerative insufficiency involving both leaflets // Int. Cardiol. Vasc. Thorac. Surg. 2006. Vol. 5 (Suppl 2). P. 220.