Vol. 19 No. 2 (2015)
CORONARY ARTERY DISEASES

Remote results of surgical treatment of moderate ischemic mitral regurgitation in patients with normal left ventricle function

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  • A. Cherniavsky,
  • R. Razumakhin,
  • V. Efendiev,
  • T. Ruzmatov,
  • T. Podsosnikova,
  • T. Volokitina,
  • N. Matveyeva
A. Cherniavsky
Academician Ye. Meshalkin Novosibirsk Research Institute of Circulation Pathology, 15 Rechkunovskaya Str., Novosibirsk, 630055, Russian Federation
Bio
R. Razumakhin
Academician Ye. Meshalkin Novosibirsk Research Institute of Circulation Pathology, 15 Rechkunovskaya Str., Novosibirsk, 630055, Russian Federation
Bio
V. Efendiev
Academician Ye. Meshalkin Novosibirsk Research Institute of Circulation Pathology, 15 Rechkunovskaya Str., Novosibirsk, 630055, Russian Federation
Bio
T. Ruzmatov
Academician Ye. Meshalkin Novosibirsk Research Institute of Circulation Pathology, 15 Rechkunovskaya Str., Novosibirsk, 630055, Russian Federation
Bio
T. Podsosnikova
Academician Ye. Meshalkin Novosibirsk Research Institute of Circulation Pathology, 15 Rechkunovskaya Str., Novosibirsk, 630055, Russian Federation
Bio
T. Volokitina
Academician Ye. Meshalkin Novosibirsk Research Institute of Circulation Pathology, 15 Rechkunovskaya Str., Novosibirsk, 630055, Russian Federation
Bio
N. Matveyeva
Academician Ye. Meshalkin Novosibirsk Research Institute of Circulation Pathology, 15 Rechkunovskaya Str., Novosibirsk, 630055, Russian Federation
Bio
DOI: https://doi.org/10.21688/1681-3472-2015-2-63-71

Published 2015-10-08

Keywords

  • ischemic mitral regurgitation,
  • ejection fraction

How to Cite

Cherniavsky, A., Razumakhin, R., Efendiev, V., Ruzmatov, T., Podsosnikova, T., Volokitina, T., & Matveyeva, N. (2015). Remote results of surgical treatment of moderate ischemic mitral regurgitation in patients with normal left ventricle function. Patologiya Krovoobrashcheniya I Kardiokhirurgiya, 19(2), 63–71. https://doi.org/10.21688/1681-3472-2015-2-63-71

Copyright (c) 2015 Cherniavsky A.M., Razumakhin R.A., Efendiev V.U., Ruzmatov T.M., Podsosnikova T.N., Volokitina T.L., Matveyeva N.V.

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

Background. One of the complications of coronary heart disease is ischemic mitral regurgitation (IMR). Moderate IMR remains one of the challenges in devising the tactics for its correction.
Objective. The study was aimed at comparing the results after coronary artery bypass grafting (CABG) alone and CABG with mitral valve annuloplasty (MVA) in patients with normal ejection fraction (EF) of the left ventricle (LV) or approximated one.
Methods. The study included 93 CHD patients with moderate ischemic MR and normal or close to normal LVEF. 81 patients reached a 1-year research checkpoint when this paper was being prepared. All patients were randomized into two groups. The first group included 40 patients who underwent CABG alone, the second group included 41 patients who had underwent CABG plus MVA performed by using a complete annuloplasty ring. Mean age was 61.4±7.2 years, 60 (74%) patients were male. Mean LVEF was 45% (40; 53).
Results. There was no early postoperative mortality (<30 days) in both groups. Survival at 1 year was similar in both groups: 93% in the CABG plus MVA group versus 97% in the CABG group. No statistical difference was observed in both groups. A year after surgery only 1 patient (3%) in the CABG group showed complete freedom from mitral regurgitation, while in the CABG plus MVA group there were 16 patients (42%). At 1 year after surgery, NYHA functional class of patients in the CABG plus MVA group decreased from 3 (2; 3) to 0 (0; 1) (p<0.001), while in the CABG alone group it dropped down from 3 (3; 3) to 2 (1; 2) (p<0.001).
Conclusion. The addition of MVA to CABG effectively reduces the degree of moderate ischemic MR. Both methods improve the clinical condition of patients and the quality of life 1 year after surgery.

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