Vol. 19 No. 2 (2015)
CORONARY ARTERY DISEASES

Predictors of remote mortality of CHD patients with severe left ventricular dysfunction

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  • A. Cherniavsky,
  • O. Yefremova,
  • T. Ruzmatov,
  • V. Efendiyev
A. Cherniavsky
Academician Ye. Meshalkin Novosibirsk Research Institute of Circulation Pathology, 15 Rechkunovskaya Str., Novosibirsk, 630055, Russian Federation
Bio
O. Yefremova
Academician Ye. Meshalkin Novosibirsk Research Institute of Circulation Pathology, 15 Rechkunovskaya Str., Novosibirsk, 630055, Russian Federation
Bio
T. Ruzmatov
Academician Ye. Meshalkin Novosibirsk Research Institute of Circulation Pathology, 15 Rechkunovskaya Str., Novosibirsk, 630055, Russian Federation
Bio
V. Efendiyev
Academician Ye. Meshalkin Novosibirsk Research Institute of Circulation Pathology, 15 Rechkunovskaya Str., Novosibirsk, 630055, Russian Federation
Bio
DOI: https://doi.org/10.21688/1681-3472-2015-2-49-54

Published 2015-10-08

Keywords

  • coronary artery disease,
  • left ventricular dysfunction,
  • optimal drug therapy,
  • coronary artery bypass grafting,
  • risk factors of mortality

How to Cite

Cherniavsky, A., Yefremova, O., Ruzmatov, T., & Efendiyev, V. (2015). Predictors of remote mortality of CHD patients with severe left ventricular dysfunction. Patologiya Krovoobrashcheniya I Kardiokhirurgiya, 19(2), 49–54. https://doi.org/10.21688/1681-3472-2015-2-49-54

Copyright (c) 2015 Cherniavsky A.M., Yefremova O.S., Ruzmatov T.M., Efendiyev V.U.

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

Objective. The study was designed to identify risk factors for long-term mortality in patients with coronary heart disease (CHD) and ejection fraction (EF) of the left ventricle (LV) ≤5% when performing drug therapy and surgical treatment.
Methods. This randomized prospective study involved 80 patients with coronary artery disease and severe left ventricular dysfunction, of which 40 patients received optimal drug therapy (ODT) and 40 patients underwent coronary artery bypass grafting (CABG). Both groups of patients were completely comparable in demographics, clinical and functional status, echocardiographic parameters, nature of coronary artery disease, comorbidity and volume of the drug therapy received.
Results. Hospital mortality was recorded only when patients underwent surgery. The risk factors of 7-year mortality for CHD patients with low LVEF were: IV class NYHA, a restrictive type of diastolic dysfunction, Syntax score >22 points, atrial fibrillation and ventricular arrhythmia in the drug treatment group. For patients who underwent surgery these factors included I-II class of angina pectoris, IV class NYHA, pulmonary pressure >55 mmHg, atrial fibrillation and restrictive type of diastolic dysfunction.
Conclusion. Statistically significant differences in the 7-year survival rate of patients of the two groups were not found. 

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