Vol. 16 No. 3 (2012)
CONGENITAL HEART DISEASES

Molecular features of cardiomyocytes in chemical and structural elements of infants with transposition of great arteries

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  • G. Okuneva,
  • Ye. Kliver,
  • A. Karaskov,
  • Yu. Gorbatykh,
  • A. Volkov,
  • Yu. Vlasov,
  • V. Trunova,
  • V. Zvereva
G. Okuneva
Academician E.N. Meshalkin Novosibirsk Research Institute of Circulation Pathology
Bio
Ye. Kliver
Academician E.N. Meshalkin Novosibirsk Research Institute of Circulation Pathology
Bio
A. Karaskov
Academician E.N. Meshalkin Novosibirsk Research Institute of Circulation Pathology
Bio
Yu. Gorbatykh
Academician E.N. Meshalkin Novosibirsk Research Institute of Circulation Pathology
Bio
A. Volkov
Academician E.N. Meshalkin Novosibirsk Research Institute of Circulation Pathology
Bio
Yu. Vlasov
Academician E.N. Meshalkin Novosibirsk Research Institute of Circulation Pathology
Bio
V. Trunova
Nikolaev Institute of Inorganic Chemistry SB RAS
Bio
V. Zvereva
Nikolaev Institute of Inorganic Chemistry SB RAS
Bio
DOI: https://doi.org/10.21688/1681-3472-2012-3-13-17

Published 2012-09-25

Keywords

  • CHEMICAL ELEMENTS,
  • MOLECULAR STRUCTURE OF CARDIOMYOCYTES,
  • TRANSPOSITION OF THE GREAT ARTERIES

How to Cite

Okuneva, G., Kliver, Y., Karaskov, A., Gorbatykh, Y., Volkov, A., Vlasov, Y., Trunova, V., & Zvereva, V. (2012). Molecular features of cardiomyocytes in chemical and structural elements of infants with transposition of great arteries. Patologiya Krovoobrashcheniya I Kardiokhirurgiya, 16(3), 13–17. https://doi.org/10.21688/1681-3472-2012-3-13-17

Copyright (c) 2012 Okuneva G.N., Kliver Ye.E., Karaskov A.M., Gorbatykh Yu.N., Volkov A.M., Vlasov Yu.A., Trunova V.A., Zvereva V.V.

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

Chemical elements play an important role in transposition of the great arteries (TGA). We investigated the content of chemical elements in the myocardium of patients with TGA and compared the results with the morphological and anatomical data. Also studied were samples of myocardium from infants with TGA at the age of 1 to 6 months. To study the concentration of 14 chemical elements, an X-ray method of fluorescent analysis (on the basis of synchrotron emission) was used. The morphological measurements show a decrease in the diameter of muscle fibers, reduction of the average surface of nuclei, changes in the synthesis of cardiac myosine to skeletal myosine, as well as a decrease in the nucleus-cytoplasmic factor.
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