Vol. 30 No. 3 (2026)
ACQUIRED HEART DISEASES

Immediate Outcomes of Heart Valve Prostheses with a Rapid-Deployment Sutureless Cuff versus Standard Sutured Prostheses in the Correction of Degenerative Aortic Valve Failure

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  • Sergei A. Zhurko,
  • Alexandr M. Osipov,
  • Alishir B. Gamzaev,
  • Mariya L. Kalinina,
  • Marina B. Suhova,
  • Emir Kurmanbek uulu,
  • Artem A. Golubev,
  • Dmitrii I. Lashmanov
Sergei A. Zhurko
Korolev Specialized Cardiovascular Clinical Hospital
Bio
Alexandr M. Osipov
Korolev Specialized Cardiovascular Clinical Hospital
Alishir B. Gamzaev
Scientific Research Institute – Korolev Specialized Cardiovascular Clinical Hospital, Nizhny Novgorod, Russian Federation; Privolzhsky Research Medical University, Nizhny Novgorod, Russian Federation
Bio
Mariya L. Kalinina
Korolev Specialized Cardiovascular Clinical Hospital
Bio
Marina B. Suhova
Korolev Specialized Cardiovascular Clinical Hospital
Bio
Emir Kurmanbek uulu
Privolzhsky Research Medical University
Artem A. Golubev
Clinical Cardiology Dispensary of Komi Republic
Dmitrii I. Lashmanov
Korolev Specialized Cardiovascular Clinical Hospital
DOI: https://doi.org/10.21688/1681-3472-2026-3-65-77

Published 2026-10-21

Keywords

  • бесшовные протезы; время пережатия аорты; длительность искусственного кровообращения; клапаны быстрого развертывания; присоединяемая манжета с бесшовной фиксацией; протезирование аортального клапана

How to Cite

Zhurko, S. A., Osipov, A. M. ., Gamzaev, A. . B. ., Kalinina, M. L., Suhova, M. B., Kurmanbek uulu, E. ., Golubev, A. A., & Lashmanov, D. I. (2026). Immediate Outcomes of Heart Valve Prostheses with a Rapid-Deployment Sutureless Cuff versus Standard Sutured Prostheses in the Correction of Degenerative Aortic Valve Failure. Patologiya Krovoobrashcheniya I Kardiokhirurgiya, 30(3), 65–77. https://doi.org/10.21688/1681-3472-2026-3-65-77

Copyright (c) 2026 Zhurko et al.

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

Introduction: Sutureless valves represent an alternative approach to aortic valve replacement, enabling rapid prosthesis implantation without placement of multiple interrupted sutures.

Objective: To compare prostheses with a rapid-deployment sutureless cuff with standard sutured prostheses in patients with degenerative aortic valve disease.

Methods: This prospective, single-centre, non-randomised pilot study
included 105 patients who underwent aortic valve replacement between January 2022 and March 2024. Patients were allocated to three groups: a rapid-deployment sutureless cuff with mechanical or biological valve cartridges (n = 35), the Medeng-2 mechanical prosthesis (n = 41), and the UniLine biological prosthesis (n = 29). The primary endpoints were allcause and prosthesis-related mortality within 30 days. Secondary endpoints included mean transprosthetic pressure gradients at discharge and the frequency and nature of complications.

Results: The groups were comparable for most preoperative characteristics,
including EuroSCORE II (p = 0.213). Statistically significant differences
were observed in age and left ventricular ejection fraction, reflecting
clinical selection rather than systematic differences in operative risk. Cardiopulmonary bypass and aortic cross-clamp times were significantly
shorter in the sutureless cuff group (p < 0.001). Thirty-day all-cause mortality
was 8.6% (3/35) in the RDSC group, 7.3% (3/41) in the Medeng-2 group, and 3.3% (1/29) in the UniLine group (p = 0.78). Permanent pacemaker implantation rates were 8.8%, 0%, and 3.3%, respectively (p = 0.18). At discharge, mean pressure gradients were lower in the sutureless cuff group than in the mechanical prosthesis group.

Conclusion: Preliminary findings from this pilot study suggest that a rapid-deployment sutureless cuff reduces operative time and provides satisfactory early haemodynamic outcomes. Further studies are required to confirm safety with respect to rare complications and to evaluate longterm outcomes.

Received 18 April 2026. Revised 22 June 2026. Accepted 4 August 2026.

Informed consent
The patient’s informed consent to use the records for medical purposes is obtained.

Funding
The study did not have sponsorship.

Conflict of interest
The authors declare no conflict of interest.

Contribution of the authors
Conception and study design: S.A. Zhurko, A.M. Osipov, A.B. Gamzaev, A.A. Golubev

Data collection and analysis: A.M. Osipov, M.L. Kalinina, M.B. Sukhova, E. Kurmanbek uulu, D.I. Lashmanov

Statistical analysis: A.M. Osipov

Drafting the article: S.A. Zhurko, A.M. Osipov, A.B. Gamzaev

Critical revision of the article: S.A. Zhurko, A.M. Osipov, A.B. Gamzaev

Final approval of the version to be published: all authors

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