Vol. 29 No. 4 (2025): Patologiya krovoobrashcheniya i kardiokhirurgiya
EXPERIMENTAL STUDIES

Assessment of a new technology for surface modification of the bearing unit of a domestically produced mechanical circulatory support device

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  • Maksim O. Zhulkov,
  • Mikhail S. Nosov,
  • Andrey V. Protopopov,
  • Yaroslav M. Smirnov,
  • Alexander G. Makaev,
  • Alexey D. Limanskiy,
  • Dmitry A. Sirota
Maksim O. Zhulkov
Meshalkin National Medical Research Center of the Ministry of Health of the Russian Federation, 15 Rechkunovskaya St., Novosibirsk, 630055, Russia;
Mikhail S. Nosov
Institute of Biophysics of the Future. Laboratory of Advanced Solutions in Biophysics and Automation, Institutsky lane, 9, bld. 7, “Fiztekh.BIO” building, Dolgoprudny, Russia.
Andrey V. Protopopov
Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation
Yaroslav M. Smirnov
Meshalkin National Medical Research Center of the Ministry of Health of the Russian Federation, 15 Rechkunovskaya St., Novosibirsk, 630055, Russia;
Alexander G. Makaev
Meshalkin National Medical Research Center of the Ministry of Health of the Russian Federation, 15 Rechkunovskaya St., Novosibirsk, 630055, Russia;
Alexey D. Limanskiy
Meshalkin National Medical Research Center of the Ministry of Health of the Russian Federation, 15 Rechkunovskaya St., Novosibirsk, 630055, Russia;
Dmitry A. Sirota
Meshalkin National Medical Research Center of the Ministry of Health of the Russian Federation, 15 Rechkunovskaya St., Novosibirsk, 630055, Russia;
DOI: https://doi.org/10.21688/1681-3472-2025-4-13-24

Published 2026-01-21

Keywords

  • coatings; hemocompatibility; mechanical circulatory support

How to Cite

Zhulkov, M. O. Z., Nosov, M. S. N., Protopopov, A. V. P., Smirnov, Y. M. S., Makaev, A. G. M., Limanskiy, A. D. L., & Sirota, D. A. S. (2026). Assessment of a new technology for surface modification of the bearing unit of a domestically produced mechanical circulatory support device. Patologiya Krovoobrashcheniya I Kardiokhirurgiya, 29(4), 13–24. https://doi.org/10.21688/1681-3472-2025-4-13-24

Copyright (c) 2026 Максим Олегович Жульков, Михаил Сергеевич Носов, Андрей Владимирович Протопопов, Ярослав Максимович Смирнов, Александр Геннадьевич Макаев, Алексей Дмитриевич Лиманский, Дмитрий Андреевич Сирота

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

Background: This study investigated the efficacy of surface modification for blood-contacting friction pairs in a domestically produced axial pump of a left ventricular assist device (LVAD) by applying a hydrocarbon coating doped with silicon and oxygen (a-C:H:SiOx). The LVAD represents a part of the medical product “Universal Complex for Mechanical Support of the Left and Right Ventricular Pump Function 'STREAM CARDIO'”.

Objective: This study was aimed to in vivo experimental assessment of endurance and hemocompatibility of the domestically produced axial pump “STREAM CARDIO” with applied a-C:H:SiOx coating.

Methods: The coating was applied using plasma-enhanced chemical vapor deposition. A series of subacute experiments on pigs (n = 3) lasting up to 5 days were conducted to assess pump performance and hemostasis parameters.

Results: The experiments demonstrated stable device operation with a flow rate of 4.5 [4.0; 5.0] L/min at 7222 [6900; 7500] rpm. No significant increase in power consumption of left ventricular assist device and thrombus formation was revealed.

Conclusion: The tested coating has demonstrated high endurance and hemocompatibility in experiments.

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