Vol. 25 No. 4 (2021)
CORONARY ARTERY DISEASES

Quality of life after myocardial re-vascularisation in patients with acute coronary syndrome during the coronavirus disease 2019 pandemic: a prospective observational study

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  • A.S. Klinkova,
  • O.V. Kamenskaya,
  • I.Yu. Loginova,
  • A.M. Chernyavskiy,
  • V.V. Lomivorotov
A.S. Klinkova
Meshalkin National Medical Research Center, Novosibirsk
Bio
O.V. Kamenskaya
Meshalkin National Medical Research Center, Novosibirsk
I.Yu. Loginova
Meshalkin National Medical Research Center, Novosibirsk
A.M. Chernyavskiy
Meshalkin National Medical Research Center, Novosibirsk
V.V. Lomivorotov
Meshalkin National Medical Research Center, Novosibirsk; Novosibirsk State University, Novosibirsk
DOI: https://doi.org/10.21688/1681-3472-2021-4-64-75

Published 2021-12-28

Keywords

  • COVID-19,
  • myocardial re-vascularisation,
  • quality of life

How to Cite

Klinkova, A., Kamenskaya, O., Loginova, I., Chernyavskiy, A., & Lomivorotov, V. (2021). Quality of life after myocardial re-vascularisation in patients with acute coronary syndrome during the coronavirus disease 2019 pandemic: a prospective observational study. Patologiya Krovoobrashcheniya I Kardiokhirurgiya, 25(4), 64–75. https://doi.org/10.21688/1681-3472-2021-4-64-75

Copyright (c) 2021 Klinkova A.S., Kamenskaya O.V., Loginova I.Yu., Chernyavskiy A.M., Lomivorotov V.V.

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

Aim. To study the quality of life and how it is influenced by different factors in the long term after myocardial re-vascularisation in patients with coronary artery disease who had acute coronary syndrome during the coronavirus disease 2019 (COVID-19) pandemic.
Methods. We examined 658 patients with coronary artery disease and acute coronary syndrome (mean age 66.4 ± 4.3 years). Percutaneous coronary intervention (600 patients) and coronary artery bypass grafting with cardio-pulmonary bypass (58 patients) were performed. Six months after myocardial re-vascularisation, we assessed patients' quality of life using the SF-36 questionnaire. We identified factors that affect the quality of life using multivariate regression analysis.
Results. After myocardial revascularisation, the patients had a reduced overall indicator of physical health (< 40 points). The overall indicator of psycho-emotional health was higher than physical (p < 0.002) but did not exceed 50 points. We noted the adverse effect of COVID-19 (regardless of disease severity) on the assessment. Also, COVID-19 was associated with increased anxiety. A history of concomitant diabetes mellitus, obesity, stroke and percutaneous coronary intervention had a negative effect on the overall indicators of physical and mental health.
Conclusion. Patients with coronary artery disease who had acute coronary syndrome after myocardial re-vascularisation are characterised by reduced indicators of physical and average indicators of mental health in the long term. COVID-19, regardless of disease severity, has a negative impact on patients' general state of health, social activity and emotional background. A history of diabetes mellitus, obesity, stroke and percutaneous coronary intervention adversely affects the physical and mental health indicators.

Received 4 August 2021. Revised 31 August 2021. Accepted 1 September 2021.

Funding: This work was carried out within the framework of the state task of the Ministry of Health of the Russian Federation (No. 121031300225-8).

Conflict of interest: Authors declare no conflict of interest.

Contribution of the authors
Conception and study design: O.V. Kamenskaya, V.V. Lomivorotov
Data collection and analysis: A.S. Klinkova
Statistical analysis: A.S. Klinkova
Drafting the article: A.S. Klinkova, I.Yu. Loginova
Critical revision of the article: O.V. Kamenskaya, A.M. Chernyavskiy
Final approval of the version to be published: A.S. Klinkova, O.V. Kamenskaya, I.Yu. Loginova, A.M. Chernyavskiy, V.V. Lomivorotov

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